INCREASES BRAIN NEUROSTEROID BIOSYNTHESIS

• The mitochondrial translocator protein controls neurosteroid synthesis
• Neurosteroids are potent positive allosteric modulators at GABAA receptors
• Etifoxine increases the production of allopregnanolone and other neurosteroids.
• Neurosteroids are clinically anxiolytic, anti-depressant, and anti-epileptic.

NEUROSTEROIDS NATURALLY ENHANCED

Animal models studying etifoxine have shown a 10x increase in endogenous neurosteroids.

“The most effective known compound to enhance the synthesis of brain neurosteroids”

Chart Reference: Pharmacopsychiatry Journal, 2015

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