The human brain is a complex network of billions of interconnected cells, organized in many networks communicating with one another. Some CNS disorders arise from dysregulation in the modulation of these networks, either by altered levels of signaling molecules like neurosteroids or the receptors they target.

Boosting the brain’s natural production of neurosteroids to restore normal neurosteroid tone represents a better and potentially more natural therapeutic approach for the treatment of these complex CNS disorders.

Drugs that naturally enhance the brain’s concentration of neurosteroids produce a full spectrum of pharmacological actions, unlike unnatural synthetic versions, which only target specific receptors. Key to natural enhancement of neurosteroids is the preservation of the spatial and temporal nature of neurotransmission. This results in less side effects, because the brain controls, with exquisite precision, what, where and when neurosteroids are being produced, unlike drugs that are given exogenously.